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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LBR All Species: 19.09
Human Site: Y385 Identified Species: 30
UniProt: Q14739 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14739 NP_002287.2 615 70703 Y385 I G T F D L K Y F C E L R P G
Chimpanzee Pan troglodytes XP_514234 615 70705 Y385 I G T F D L K Y F C E L R P G
Rhesus Macaque Macaca mulatta XP_001094360 615 70652 Y385 I G T F D L K Y F C E L R P G
Dog Lupus familis XP_547512 618 70479 Y388 I G T F D L K Y F C E L R P G
Cat Felis silvestris
Mouse Mus musculus Q3U9G9 626 71422 F396 L G A F D L K F F C E L R P G
Rat Rattus norvegicus O08984 620 70706 F390 I G A F D L K F F C E L R P G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514211 617 70577 Y387 I G T F D L K Y F C E L R P G
Chicken Gallus gallus P23913 637 73480 K377 R I G S F D L K Y F C E L R P
Frog Xenopus laevis Q7ZXH1 473 54804 I269 G Q V T N S M I L V N V L Q A
Zebra Danio Brachydanio rerio Q7SXF1 478 55171 L275 Y V T N S M I L V N V L Q A V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8MLV1 741 83167 K491 W L G R V D W K Q F Q Y R L S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786536 578 65964 N364 L F L W A L I N M A C L T K V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9LDR4 369 41895 K166 I N L S I L A K S V Q D G S L
Baker's Yeast Sacchar. cerevisiae P32462 438 50597 H235 I N L S C L H H H Y L K T G K
Red Bread Mold Neurospora crassa P38670 490 54704 T287 M E P A V L T T M D I T T D G
Conservation
Percent
Protein Identity: 100 99 98.2 82.3 N.A. 78.7 79.5 N.A. 78.1 65.4 30.4 29.9 N.A. 23 N.A. N.A. 44.2
Protein Similarity: 100 99.8 99.3 89.4 N.A. 88 87.4 N.A. 87.3 77.3 45.8 46.1 N.A. 38.7 N.A. N.A. 59.1
P-Site Identity: 100 100 100 100 N.A. 80 86.6 N.A. 100 0 0 13.3 N.A. 6.6 N.A. N.A. 13.3
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 100 6.6 13.3 26.6 N.A. 13.3 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 28.2 30.5 20.6
Protein Similarity: N.A. N.A. N.A. 40.9 43.2 34.8
P-Site Identity: N.A. N.A. N.A. 13.3 13.3 13.3
P-Site Similarity: N.A. N.A. N.A. 20 20 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 14 7 7 0 7 0 0 7 0 0 0 7 7 % A
% Cys: 0 0 0 0 7 0 0 0 0 47 14 0 0 0 0 % C
% Asp: 0 0 0 0 47 14 0 0 0 7 0 7 0 7 0 % D
% Glu: 0 7 0 0 0 0 0 0 0 0 47 7 0 0 0 % E
% Phe: 0 7 0 47 7 0 0 14 47 14 0 0 0 0 0 % F
% Gly: 7 47 14 0 0 0 0 0 0 0 0 0 7 7 54 % G
% His: 0 0 0 0 0 0 7 7 7 0 0 0 0 0 0 % H
% Ile: 54 7 0 0 7 0 14 7 0 0 7 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 47 20 0 0 0 7 0 7 7 % K
% Leu: 14 7 20 0 0 74 7 7 7 0 7 60 14 7 7 % L
% Met: 7 0 0 0 0 7 7 0 14 0 0 0 0 0 0 % M
% Asn: 0 14 0 7 7 0 0 7 0 7 7 0 0 0 0 % N
% Pro: 0 0 7 0 0 0 0 0 0 0 0 0 0 47 7 % P
% Gln: 0 7 0 0 0 0 0 0 7 0 14 0 7 7 0 % Q
% Arg: 7 0 0 7 0 0 0 0 0 0 0 0 54 7 0 % R
% Ser: 0 0 0 20 7 7 0 0 7 0 0 0 0 7 7 % S
% Thr: 0 0 40 7 0 0 7 7 0 0 0 7 20 0 0 % T
% Val: 0 7 7 0 14 0 0 0 7 14 7 7 0 0 14 % V
% Trp: 7 0 0 7 0 0 7 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 0 0 34 7 7 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _